SASdb

Alternative splicing events (ASE) is a fundamental mechanism contributing to transcriptomic and proteomic diversity in eukaryotes, playing a pivotal role in numerous biological processes. SASdb is a database dedicated to the study of human sex-biased alternative splicing events. Through large-scale and in-depth analysis of transcriptome data from 22 types of human tissues, it reveals widely existing sex-biased splicing patterns, providing new insights into molecular differences between the two sexes.

Through the analysis of 1,044 human samples about 22 tissues, 2,951,059 ASEs (alternative splicing events) were detected.

The identification of 136,917 ASEs showed significant gender differences (P value < 0.05).

There are 14,093 genes associated with sex-biased ASEs, which were used for relevant functional analysis in different tissues.

Overview of SASdb

The figure above shows an overview of the data in SASdb. The bar chart in the top half shows the number of various types of ASE in each tissue, and the bar chart in the bottom half shows the number of ase by recognition types. The lines in the figure show the number of SAS (sex-biased alternative splicing) and DG (differential gene) in each tissue.
Clicking on the tissue in the horizontal coordinate above, and the details page of the corresponding tissue will pop up. More detailed information on gender differences will be presented here.
Click on the legend in the diagram can select the information you want to show.